Upper Mississippi River Cruise

The dramatic landscapes of the Upper Mississippi River have long inspired artists, writers, and steamboat passengers. It was here that literary great Mark Twain used the majestic river and its scenic bluffs as the settings in his most popular works. Visit his boyhood home in Hannibal, where the characters of Huck Finn, Tom Sawyer, and Becky Thatcher come to life. Explore the beautiful gardens and historic homes of La Crosse. Get close to nature in Red Wing as you witness a variety of bald eagle nests. Enjoy a guided tour of the Black Hawk State Historic Site which celebrates the story of the Sauk and Meskwaki Indians who once called Davenport home.

Ask about our Current Savings and our Complimentary Pre-cruise Packages which include a premium hotel stay and transportation to the ship. Click the Schedules & Rates tab for details.

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Cruise Itinerary

Day
Ports of Call
1
St. Louis, MO
2
Hannibal, MO
3
Day of River Cruising
4
Davenport, IA
5
Dubuque, IA
6
La Crosse, WI
7
Red Wing, MN
8
St. Paul, MN

Upper Mississippi River Cruise

From St. Louis to St. Paul, enjoy the historic landmarks and diverse blend of arts and entertainment. Explore destinations such as Hannibal, Davenport, and La Crosse, each offering its own fascinating story and unique culture.

Ports of Call

  • St. Louis, MO
  • St. Louis, MO
  • Hannibal, MO
  • Davenport, IA
  • Dubuque, IA
  • La Crosse, WI
  • Red Wing, MN
  • St. Paul, MN

Day by Day

Reverse itineraries available. Please contact your Cruise Specialist for your specific Day By Day agenda.

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Pre-Cruise
St. Louis, MO

Each Mississippi itinerary comes complete with a Complimentary Pre-Cruise Package, providing you with a seamless way to board the ship and explore the local area. Arrive the day before your scheduled cruise date and American Cruise Lines will handle the rest. The package includes a premium hotel stay, where you can enjoy the city at your leisure. On the morning of the cruise, meet in the hotel lobby after breakfast and we will transport you to the ship to begin your cruise. All luggage will be brought directly from the hotel and placed in your stateroom aboard the ship.

*Pre-Cruise Package is not available for reservations made within 30 days of cruise date.

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Day  1
St. Louis, MO

St. Louis is sure to win you over. Admire the scenic riverfront, highlighted by the majestic Gateway Arch, the largest manmade monument in the U.S. Enjoy St. Louis’ many world-class attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s most popular public gardens.

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Missouri History Museum

Enjoy a guided tour through two of the museum’s most popular exhibits; The 1904 World’s Fair: Looking Back at Looking Forward, an event that attracted over 200,000 visitors to the opening day and Route 66: Main Street Through St. Louis, a roadway which played an important role in American History not only in fact but in myth. Learn about the companies and tourist traps that travelers had to pass through.

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Discover St. Louis Tour - Complimentary Excursion

Join others on this narrated tour of downtown St. Louis, the riverfront, Citygarden, and the historic neighborhoods of Soulard and Lafayette Square. Delight in an additional driving tour of St. Louis' 1,371 acre Forest Park, known as a natural oasis in an urban environment. Visit Anheuser Busch Brewery for a stables-only tour (if available) to see the historic stables built in 1885 and the world-famous Clydesdale horses.

*Note: This tour is only offered on cruises ending in St. Louis, MO.
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Day  2
Hannibal, MO

Hannibal, “America’s Hometown,” is a place where you can rediscover adventures from Mark Twain’s era. Tom Sawyer and Huck Finn come to life in this charming Missouri town, where you can run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. The downtown area is a thriving haven for artisans filled with specialty shops unique to Hannibal.

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Mark Twain Boyhood Home & Museum - Complimentary Excursion

As you arrive in Hannibal, the boyhood home of famous author Mark Twain, relive the author’s experiences that heavily influenced his writings. Visit the actual home that Mark Twain grew up in, which is surrounded by the legendary whitewashed fence of Tom Sawyer. The vivid stories told by Mark Twain come to life at this interactive museum as you explore the homes and grounds of Becky Thatcher and Huck Finn. Stop at the Interpretive Center, home to 15 original Normal Rockwell paintings, the Becky Thatcher House, the Huck Finn Home, and the Tom and Huck Statue at the foot of Cardiff Hill.

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Rockcliffe Mansion & Trolley Tour

Relive the adventures of Mark Twain’s time in Hannibal during a historic trolley tour. Your experienced guide will share the history of Hannibal and take you to places of historical significance, including the Rockcliffe Mansion, an amazing 13,500 square foot American castle built to overlook the mighty Mississippi River. This tour will highlight many of the exciting places which inspired Mark Twain’s famous tales.

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Day  3
Day of River Cruising

Take in the beauty of the river as you make your way from Hannibal to Davenport. Join other passengers in our beautiful common areas or simply relax on the sun deck.

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Day  4
Davenport, IA

Voted one of the Most Livable Small Cities in America, Davenport is often described as a lively, active city with a hometown feel. This city features the largest agricultural exhibit in the world. Music enthusiasts will enjoy Davenport’s many music festivals, including the Mississippi Valley Blues Festival, The Mississippi Valley Fair, and the Bix Beiderbecke Memorial Jazz Festival which is dedicated to native Jazz musician Bix Beiderbecke.

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John Deere Pavilion & Davenport City Tour - Complimentary Excursion

Enjoy a stop at the John Deere Pavilion and Store. The company’s rich heritage is chronicled in exhibits, interactive touch screen displays, and equipment dating back nearly 175 years, including antique tractors, and giant modern combines. Continue on a narrated city tour of Davenport and learn about the Rock Island Arsenal, Davenport native Bix Biederbecke’s contribution to Jazz, Rock Island’s 1920’s “Crime Lord” John Looney, the area’s beautiful college campuses, and the city’s Native American history.

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Black Hawk State Historic Site

Enjoy a guided tour of the Hauberg Indian Museum. Located in the Black Hawk State Historic Site, this museum interprets the story of the Sauk and Meskwaki Indians who once called it home. During the tour, view full-size replicas of Sauk winter and summer homes, dioramas with life-size figures of the Sauk and Meskwaki Indians and traditional artifacts, including authentic trade goods and jewelry.

 

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Day  5
Dubuque, IA

A “Masterpiece on the Mississippi,” Dubuque is among the oldest settlements west of the Mississippi River. Take a ride on the Fenelon Place Elevator, the world’s shortest and steepest scenic railway or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through the whimsical downtown area, and visit the national Mississippi River Museum and Aquarium.

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Delight in Dubuque

Step back in time and experience the elegance of Victorian-era Dubuque during a tour through the town’s many historic attractions. Learn about the architecture, families, and events that made 19th-century Dubuque such a unique treasure. Your guide will lead you through Dubuque's beautiful historic sites, including the Mathias Ham House and The Old Jail Museum.

 

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National Mississippi River Museum & Aquarium - Complimentary Excursion

Take an entertaining and informative journey along the mighty Mississippi at the National Mississippi River Museum and Aquarium. On this guided tour, you will discover the lives of the pioneers, explorers, and artists who lived along the Mississippi River and get close to nature as you make your way through six large aquariums. The museum’s interactive exhibits will give you an inside look into the Mississippi River's past, present and future.

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Day  6
La Crosse, WI

Step into 19th-century America in La Crosse, located on the banks of three captivating rivers. La Crosse is home to Riverside Park, where you will enjoy beautiful gardens, an outdoor performance center, and inspiring sculptures.

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Hixon House & La Crosse City Tour

Take a narrated tour of this wonderful city. Discover the historic downtown with its late 19th- and early 20th-century buildings as well as the well-preserved residential neighborhoods. Gain insight into LaCrosse’s development from the boomtown riverboat days through the roaring ‘20s, to the challenges and opportunities of the 21st century. Visit the historic Hixon House, an authentic Victorian home which has retained 90% of its original furnishings and is a designated Historic Landmark. 

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La Crosse Queen Eco Cruise

Cruise along the scenic Mississippi River on a classic paddlewheeler as your tour guide highlights the current and historical facts about the area and tests your knowledge with trivia along the way. Witness some of the most beautiful views in the Midwest including native wildlife and steep bluffs on the river. Learn about the locking process while cruising past the Lock & Dam No. 7 in Dresbach, MN.

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Day  7
Red Wing, MN

Nestled among the scenic bluffs of the upper Mississippi River, Red Wing's beauty has inspired artisans, craftspeople, and artists for over 150 years. Red Wing delivers a diverse blend of arts, entertainment, and activities for your pleasure. Enjoy a show at the historic Sheldon Performing Arts Theatre or observe the beauty of nature at one of Red Wing’s 38 parks.

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Red Wing City Tour & Pottery Museum - Complimentary Excursion

Travel back in time as you tour the beautiful city of Red Wing. Led by our local expert guide, view some of the most impressive Victorian homes of the period as well as the historic St. James Hotel. Visit the Pottery Museum of Red Wing and admire the numerous true vintage pieces on site such as stoneware, dinnerware, folk art and more! 

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National Eagle Center - Complimentary Excursion

Witness bald and golden eagles like never before – face to face! The National Eagle Center offers a unique viewing opportunity that brings visitors within a few feet of these majestic creatures with no barrier in between. This is an experience like no other, and one you will never forget.

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Day  8
St. Paul, MN

St. Paul is a thrilling river town. History buffs will enjoy a walking tour of Summit Avenue, which showcases gorgeous historic mansions built in the late 1800’s. St. Paul’s enchanting art galleries, world class museums, and entertaining stage performances will capture your imagination. End the day by visiting Mounds Park, where visitors are treated to a beautiful panoramic view of the city.

Queen of the Mississippi

Built in 2015, Queen of the Mississippi offers an authentic paddlewheeler experience with all the comforts of home. Guests can enjoy large staterooms with private balconies, hotel-style bathrooms, complimentary room service, WiFi, and more. Experience breathtaking scenery from the privacy of your stateroom as the Queen of the Mississippi makes its way down the legendary river. 


Click a Category

Owner's Suite

Deckplan

At a generous up to 445 sq. ft., the Owner’s Suites of Queen of the Mississippi offer the finest accommodations with unsurpassed views of the Mississippi River. With a spacious seating area and hotel-size bathrooms, each suite is a private sanctuary where you can unwind after a day of exploration in the tasteful comfort of your surroundings. Each of these suites features large sliding glass doors leading out to a private balcony, where you can enjoy the ever-changing scenery. Every modern amenity is at your fingertips, along with a desk, and spacious seating area.

AAM (Private Balcony)

Deckplan

Located on the top deck, these spacious staterooms feature scenic views of the passing landscape. At 328 sq. ft., you will enjoy all of the modern comforts that are expected of a premium hotel. These staterooms also offer full-size bathrooms and a walk-out private balcony where the grandness of the Mississippi can be appreciated.

AAC (Private Balcony)

Deckplan

Our AAC staterooms are conveniently located on the fourth deck and at 304 sq. ft. offer all of the comforts of a fine hotel. Complete with a private balcony and floor to ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape. 

AAL (Private Balcony)

Deckplan

AAL staterooms can be found on the third deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with plush seating, a full-size bathroom, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. 

AAR (Private Balcony)

Deckplan

AAR staterooms can be found on the second deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with a full-size bathroom, and a large private balcony with sliding glass doors.  

A

Deckplan

These 290 sq ft staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, all are equipped with modern amenities, full-size bathrooms, and closet space.

Single (Private Balcony)

Deckplan

Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

Single

Deckplan

A comfortable getaway, our Single staterooms offer individuals a spacious room with convenient amenities. At 203 sq. ft., all have interior entrances and large viewing windows where the sights of the Mississippi can be enjoyed.

Queen of the Mississippi Deck Plan

Deck

America

Launched in 2016, America is one of the finest Mississippi paddlewheelers ever built, introducing features never before seen on the Mississippi.  America embodies a casual ambiance and relaxed atmosphere while providing panoramic views of the passing scenery. With only 185 guests, fellow guests will quickly become new friends. 


Click a Category

Owner's Suite (Private Balcony)

Deckplan

Each Owner’s Suite on America offers the finest accommodations on the Mississippi River with unsurpassed views of the passing scenery. A spectacular up to 445 sq. ft. of space is your private sanctuary to spread out and make yourself at home. Floor to ceiling sliding glass doors lead to an expansive private balcony offering private panoramic views throughout the room. Every modern amenity is at your fingertips, along with a spacious seating area, desk, and hotel-size bathroom.

AAM (Private Balcony)

Deckplan

Located on the top deck, these spacious staterooms feature commanding views of the passing Mississippi landscape. At 328 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor to ceiling sliding glass doors with a private balcony to offer panoramic views of the Mississippi from every angle.  These staterooms also offer a sitting area, desk, and hotel-size bathrooms and are the epitome of comfort and relaxation.

AAC (Private Balcony)

Deckplan

AAC staterooms are conveniently located on the fourth deck and at 304 sq.ft offer all of the comforts of a fine hotel. Complete with a private balcony and floor to ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape.

AAL (Private Balcony)

Deckplan

AAL staterooms can be found on the third deck of America. Enjoy a luxurious 304 sq. ft. of living space that is equipped with plush seating, full-size bathrooms, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. 

AAR (Private Balcony)

Deckplan

AAR staterooms can be found on the second deck of the America. Enjoy a luxurious 304 sq. ft. of living space that is equipped with full-size bathrooms, and a private balcony with sliding glass doors.

A

Deckplan

These 290 sq. ft. staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, these staterooms are equipped with modern amenities, full-size bathrooms, and closet space.

Single (Private Balcony)

Deckplan

Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

Single

Deckplan

A comfortable getaway, our Single suites offer individuals a spacious room with convenient amenities. At 203 sq. ft., these staterooms have interior entrances and large opening viewing windows where the sights of the Mississippi can be enjoyed.

America Deck Plan

Deck

Mark Twain Cruise


Few American authors are as beloved as Samuel Clemens, better known by his pen name, Mark Twain.  On this special theme cruise, explore the river that served as his inspiration, complete with a true-to-life Mark Twain impersonator, and a stop in Hannibal, MO, Twain's hometown. The characters and locations of his literary classics The Adventures of Tom Sawyer and The Adventures of Huckleberry Finn come to life during our exclusive behind-the-scenes tour of the town, including a look at Huck Finn's house and the Becky Thatcher home.   

 

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Reserve Cruise

Fall Foliage Cruise


With ideal temperatures, and spectacular scenery, fall is the perfect time to explore the Mississippi River. From St. Louis to St. Paul, explore idyllic American towns and witness the beauty of the landscape during peak foliage season. Enjoy customized, award-winning excursions to the area’s most captivating destinations, including a visit to the boyhood home of literary great Mark Twain.

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* Prices displayed are per person based on double occupancy.

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